Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549097 | 0.86 | HPGD (0.39) | L3MBTL1HPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11552403 | 0.85 | ALDH1A1 (0.40) | L3MBTL1MEN1KMT2ATDP1HPGD | |
| SCHEMBL21925353 | 0.74 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2ATDP1HPGD | |
| SCHEMBL11546593 | 0.72 | OPRK1 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27777215 | 0.72 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2ATDP1HPGD | |
| SCHEMBL11480332 | 0.72 | SMN1; SMN2 (0.53) | L3MBTL1MEN1KMT2ATDP1HPGD | |
| SCHEMBL11547056 | 0.72 | TSHR (0.57) | L3MBTL1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7962153 | 0.72 | MAPT (0.41) | L3MBTL1MEN1KMT2ATDP1HPGD | |
| SCHEMBL1949240 | 0.71 | SMN1; SMN2 (0.51) | L3MBTL1MEN1KMT2ATDP1HPGD | |
| SCHEMBL7975645 | 0.70 | ALDH1A1 (0.40) | L3MBTL1MEN1KMT2ATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136187-A | CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4004014-A | VASODILATION, HYPOTENSIVE, ANTIARRHYTHMIA, SPASMOLYTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-18 | — | — | US | disclosed |
| US-3959292-A | HYPOTENSIVE AGENTS, CORONARY DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |