Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979650 | 0.86 | CTRB1 (0.65) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL10787497 | 0.86 | CTRB1 (0.60) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL2627373 | 0.84 | CTSK (0.59) | CTRB1ATMCTSLLMNACTSK | |
| SCHEMBL591895 | 0.84 | CTSK (0.59) | CTRB1ATMCTSLLMNACTSK | |
| SCHEMBL591894 | 0.84 | CTSK (0.59) | CTRB1ATMCTSLLMNACTSK | |
| SCHEMBL6806275 | 0.83 | ALDH1A1 (0.59) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL10612691 | 0.83 | CTRB1 (0.61) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL11555680 | 0.83 | CTSL (0.46) | CTRB1CTSLLMNACTSKTACR1 | |
| SCHEMBL764062 | 0.83 | CTSL (0.68) | CTRB1CTSLCTSKTACR1CTSS | |
| SCHEMBL10250520 | 0.83 | CTSL (0.68) | CTRB1CTSLCTSKTACR1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140788-A | ANTITUMOR AGENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-02-20 | — | — | US | disclosed |