Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17080224 | 0.80 | LMNA (0.61) | ALDH1A1CASP6KMT2ALMNAKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL28165768 | 0.78 | VCAM1 (0.74) | ALDH1A1VCAM1SMN1; SMN2CASP6KMT2A | |
| SCHEMBL9538378 | 0.77 | USP7 (0.59) | ALDH1A1PDE7ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL4003277 | 0.77 | LMNA (0.68) | ALDH1A1CASP6KMT2ALMNAKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL30234086 | 0.76 | VCAM1 (0.77) | ALDH1A1VCAM1CASP6KMT2ALMNA | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL6101 | 0.76 | VCAM1 (0.77) | ALDH1A1VCAM1CASP6KMT2ALMNA | |
| SCHEMBL875772 | 0.75 | PDE7A (0.78) | ALDH1A1PDE7ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL31272173 | 0.75 | PDE7A (0.78) | ALDH1A1PDE7ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL2028311 | 0.75 | SLC6A2 (0.68) | ALDH1A1PDE7ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL29140441 | 0.75 | CASP6 (0.68) | ALDH1A1CASP6LMNAPOLBHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177257-A | ANTIANAPHYLACTIC AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4145350-A | ANTIALLERGENS, TETRAZOLYL- SUBSTITUTED | BURROUGHS WELLCOME CO. (US) | 1979-03-20 | — | — | US | disclosed |