Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547754 | 0.94 | RAB9A (0.63) | MAPTGAARAB9AKDM4ETDP1 | |
| SCHEMBL11413768 | 0.82 | PDE5A (0.34) | TDP1MAPK1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL11548693 | 0.76 | TSHR (0.46) | MAPTGAATHRBRECQLCA1 | |
| SCHEMBL626632 | 0.72 | ALDH1A1 (0.43) | MAPTGAATDP1MAPK1NPSR1 | |
| SCHEMBL28831642 | 0.71 | MAPT (0.52) | MAPTGAARAB9AKDM4ETDP1 | |
| SCHEMBL11547917 | 0.70 | ALDH1A1 (0.59) | MAPTGAAKDM4ETDP1THRB | |
| SCHEMBL1459772 | 0.69 | MAPT (1.00) | MAPTGAARAB9AKDM4ETDP1 | |
| SCHEMBL39057 | 0.69 | MAPT (1.00) | MAPTGAARAB9AKDM4ETDP1 | |
| SCHEMBL851498 | 0.69 | RAB9A (0.70) | MAPTGAARAB9AKDM4ETDP1 | |
| 1,4-Dimethoxybenzene SCHEMBL21802643 | 0.68 | CA1 (1.00) | MAPTGAARAB9AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989066-B | Preparation method of indomethacin | 暨明医药科技（苏州）有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-114989066-A | Preparation method of indometacin | 暨明医药科技（苏州）有限公司 | 2022-09-02 | — | — | CN | disclosed |
| US-4163015-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4138405-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-06 | — | — | US | disclosed |