Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413768 | 0.87 | PDE5A (0.34) | TSHRALDH1A1HSD17B10ALOX15PDE5A | |
| SCHEMBL626632 | 0.77 | ALDH1A1 (0.43) | TSHRALDH1A1HSD17B10TP53CYP3A4 | |
| SCHEMBL7694989 | 0.76 | ALDH1A1 (0.39) | TSHRAPPALDH1A1RECQLHSD17B10 | |
| SCHEMBL11548366 | 0.76 | MAPT (0.52) | ALDH1A1RECQLCA12CA1CA2 | |
| SCHEMBL11547917 | 0.74 | ALDH1A1 (0.59) | TSHRALDH1A1RECQLHSD17B10CYP3A4 | |
| SCHEMBL153943 | 0.72 | TSHR (0.67) | TSHRAPPALDH1A1RECQLHSD17B10 | |
| SCHEMBL12345573 | 0.71 | KDM4E (0.50) | TSHRAPPALDH1A1HPGDMAPT | |
| SCHEMBL7609190 | 0.71 | SLC6A2 (0.48) | — | |
| SCHEMBL11547754 | 0.71 | RAB9A (0.63) | APPALDH1A1RECQLHSD17B10THRB | |
| SCHEMBL11550405 | 0.71 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163015-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4138405-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-06 | — | — | US | disclosed |