Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626632 | 0.77 | ALDH1A1 (0.43) | SLC6A2CTSDJAK2 | |
| SCHEMBL9469956 | 0.76 | NPC1 (0.43) | RAD52MAP4K4 | |
| SCHEMBL10569077 | 0.73 | SLC6A2 (0.46) | SLC6A2CTSDMDM2TAAR1RAD52 | |
| SCHEMBL11548693 | 0.71 | TSHR (0.46) | — | |
| SCHEMBL8538989 | 0.70 | KDR (0.37) | — | |
| SCHEMBL11547917 | 0.70 | ALDH1A1 (0.59) | SLC6A2JAK2 | |
| SCHEMBL7611639 | 0.69 | SLC6A2 (0.50) | SLC6A2CTSDMAP4K4JAK2TYK2 | |
| SCHEMBL9791981 | 0.67 | AOC1 (0.37) | RAD52 | |
| SCHEMBL7608055 | 0.67 | TGFBR1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL7610830 | 0.67 | SLC6A2 (0.49) | SLC6A2CTSDMAP4K4JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1184969-C | Use of unsubstd and substd. N-(pyrrol-1-yl) pyridinamines as anticonvulsant agents | AVENTIS PHARMA INC (US) | 2005-01-19 | — | — | CN | claimed |
| EP-0840609-B1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | AVENTIS PHARMA INC (US) | 2002-06-05 | — | — | EP | claimed |
| CN-1191486-A | Use of unsubstituted and substituted N- (pyrrol-1-yl) pyridinamines as anticonvulsants | HOECHST MARION ROUSSEL INC (US) | 1998-08-26 | — | — | CN | claimed |
| US-5776955-A | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents | HOECHST MARION ROUSSEL, INC. | 1998-07-07 | — | — | US | claimed |
| EP-0840609-A1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| WO-1997004777-A1 | USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-13 | — | — | WO | claimed |
| US-4900742-A | N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-02-13 | — | — | US | claimed |
| EP-0226099-A2 | N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1987-06-24 | — | — | EP | claimed |
| CN-1184969-C | Use of unsubstd and substd. N-(pyrrol-1-yl) pyridinamines as anticonvulsant agents | AVENTIS PHARMA INC (US) | 2005-01-19 | — | — | CN | disclosed |
| EP-0840609-B1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | AVENTIS PHARMA INC (US) | 2002-06-05 | — | — | EP | disclosed |
| CN-1191486-A | Use of unsubstituted and substituted N- (pyrrol-1-yl) pyridinamines as anticonvulsants | HOECHST MARION ROUSSEL INC (US) | 1998-08-26 | — | — | CN | disclosed |
| US-5776955-A | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents | HOECHST MARION ROUSSEL, INC. | 1998-07-07 | — | — | US | disclosed |
| EP-0840609-A1 | USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997004777-A1 | USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-13 | — | — | WO | disclosed |
| US-5039687-A | Learning enhancement, cognition activation | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5032599-A | Learning enhancement | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-07-16 | — | — | US | disclosed |
| US-4900742-A | N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4792562-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-20 | — | — | US | disclosed |
| US-4752610-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-06-21 | — | — | US | disclosed |
| EP-0226099-A2 | N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1987-06-24 | — | — | EP | disclosed |