Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626632 | 0.72 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| SCHEMBL7694989 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL11548693 | 0.71 | TSHR (0.46) | ALDH1A1HSD17B10TSHRCYP3A4KMT2A | |
| SCHEMBL11547917 | 0.70 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL12770885 | 0.68 | HPGD (0.53) | ALDH1A1HSD17B10KMT2AKDM4EPOLB | |
| SCHEMBL234461 | 0.68 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL7609190 | 0.67 | SLC6A2 (0.48) | — | |
| SCHEMBL655572 | 0.67 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL11548366 | 0.67 | MAPT (0.52) | ALDH1A1HTTTDP1KMT2APKM | |
| SCHEMBL8005268 | 0.66 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRCYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163015-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4138405-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-06 | — | — | US | disclosed |