Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250668 | 0.75 | GAA (0.44) | OPRM1ALDH1A1HTTOPRD1OPRK1 | |
| SCHEMBL11547438 | 0.71 | TSHR (0.39) | OPRM1ALDH1A1HTTL3MBTL1MAPT | |
| SCHEMBL6081939 | 0.69 | LMNA (0.51) | OPRM1ALDH1A1HTTL3MBTL1OPRD1 | |
| SCHEMBL3314415 | 0.68 | ALDH1A1 (0.40) | OPRM1ALDH1A1HTTL3MBTL1SLC6A4 | |
| SCHEMBL10818064 | 0.68 | OPRM1 (0.44) | OPRM1ALDH1A1OPRD1OPRK1SLC22A1 | |
| SCHEMBL17792929 | 0.68 | ALDH1A1 (0.47) | OPRM1ALDH1A1HTTL3MBTL1SLC22A1 | |
| SCHEMBL11811780 | 0.68 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1PKMMAPTPOLB | |
| SCHEMBL11256394 | 0.68 | LMNA (0.42) | ALDH1A1HTTL3MBTL1POLBLMNA | |
| SCHEMBL15978556 | 0.67 | L3MBTL1 (0.49) | OPRM1ALDH1A1HTTL3MBTL1OPRD1 | |
| SCHEMBL15977383 | 0.67 | L3MBTL1 (0.49) | OPRM1ALDH1A1HTTL3MBTL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141893-A | Decahydrocyclopent[c]azepines | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | disclosed |