Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550699 | 0.87 | SLC22A1 (0.43) | KMT2AMEN1ATML3MBTL1SMN1; SMN2 | |
| SCHEMBL11256394 | 0.78 | LMNA (0.42) | TSHRCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL11250668 | 0.76 | GAA (0.44) | TSHRCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL11548726 | 0.71 | OPRM1 (0.38) | TSHRCYP1A2CYP2C19HTTKMT2A | |
| SCHEMBL11248709 | 0.66 | HSD11B1 (0.45) | TSHRCYP1A2HSD11B1HTTKMT2A | |
| SCHEMBL11078071 | 0.65 | SLC6A4 (0.50) | KMT2AMEN1OPRM1 | |
| SCHEMBL16473787 | 0.65 | OPRM1 (0.44) | ATML3MBTL1OPRM1 | |
| SCHEMBL11248009 | 0.65 | SLC22A1 (0.43) | KMT2AMEN1ATML3MBTL1MAPT | |
| SCHEMBL28598377 | 0.65 | HTT (0.51) | TSHRCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL2610423 | 0.64 | HCRTR2 (0.45) | HTTATMHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141893-A | Decahydrocyclopent[c]azepines | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | disclosed |