Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | PEPD | P12955 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | APEX1 | P27695 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21483681 | 0.85 | TAAR1 (0.52) | KIF11TAAR1TSHRNFKB1HIF1A | |
| SCHEMBL7153255 | 0.84 | DHODH (0.54) | TAAR1TSHRNFKB1HIF1AHTR3A | |
| SCHEMBL5062623 | 0.77 | PEPD (0.80) | KIF11PEPDALDH1A1NPC1MAPT | |
| SCHEMBL4074768 | 0.77 | TAAR1 (0.80) | TAAR1TSHRNFKB1HIF1AHTR3A | |
| SCHEMBL5933189 | 0.75 | NPC1 (0.61) | KIF11PEPDALDH1A1NPC1MAPT | |
| SCHEMBL13930815 | 0.75 | ALDH1A1 (0.61) | KIF11PEPDALDH1A1NPC1MAPT | |
| SCHEMBL14281203 | 0.75 | TAAR1 (0.57) | TAAR1TSHRNFKB1HIF1AHTR3A | |
| SCHEMBL5533028 | 0.75 | KIF11 (0.89) | KIF11NFKB1PEPDKDM4EALDH1A1 | |
| SCHEMBL11575784 | 0.73 | KIF11 (0.58) | KIF11PEPDALDH1A1NPC1MAPT | |
| SCHEMBL8530522 | 0.72 | PEPD (0.59) | KIF11PEPDALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |