Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436445 | 0.83 | CHRM3 (0.36) | BRD4ATMLMNAMAPTPARK7 | |
| SCHEMBL11554969 | 0.82 | BRD4 (0.43) | BRD4LMNAMAPT | |
| SCHEMBL11440224 | 0.81 | HSD17B10 (0.41) | BRD4LMNAHSD17B10 | |
| SCHEMBL11549462 | 0.81 | HSD11B1 (0.45) | BRD4ATMLMNAMAPT | |
| SCHEMBL11426220 | 0.79 | BRD4 (0.44) | ALDH1A1BRD4LMNAMAPTBACE1 | |
| SCHEMBL11441314 | 0.78 | BRD4 (0.52) | ALDH1A1BRD4LMNAMAPTHSD17B10 | |
| SCHEMBL11428867 | 0.78 | POLB (0.41) | ALDH1A1MAPK1BRD4 | |
| SCHEMBL11549258 | 0.77 | BRD4 (0.44) | ALDH1A1MAPK1BRD4LMNAMAPT | |
| SCHEMBL21052203 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPK1MAPTBACE1 | |
| SCHEMBL29519399 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPK1MAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |