SCHEMBL734024

SCHEMBL734024

O=C1OC(=O)c2cc(I)c(Br)cc21

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
TYMS P04818 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31409205 0.83 ALOX15 (0.48) ALOX15TDP1ALDH1A1TYMS
SCHEMBL855808 0.83 ALOX15 (0.48) ALOX15TDP1ALDH1A1TYMSTSHR
SCHEMBL11383281 0.83 ALOX15 (0.48) ALOX15TDP1ALDH1A1TYMS
SCHEMBL27403656 0.78 ALOX15 (0.43) ALOX15TDP1ALDH1A1TYMSTSHR
SCHEMBL23958837 0.76 S100A4 (0.36)
SCHEMBL26978836 0.76 S100A4 (0.41)
SCHEMBL30494516 0.76 S100A4 (0.41)
SCHEMBL854455 0.73 ALOX15 (0.39) ALOX15TDP1ALDH1A1TYMSTSHR
SCHEMBL22233097 0.71 PTPRC (0.50) TDP1ALDH1A1BCHETSHR
SCHEMBL3993249 0.71 TDP1 (0.59) ALOX15TDP1ALDH1A1TYMSTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323137-A1 COMPOSITION FOR SEALING COATED ELECTRIC WIRE, AND COATED ELECTRIC WIRE TOAGOSEI CO. LTD. (JP) 2023-10-12 US disclosed
EP-3260509-B1 2-CYANOACRYLATE ADHESIVE COMPOSITION TOAGOSEI CO LTD (JP) 2021-04-07 EP disclosed
WO-2021060390-A1 COMPOSITION FOR COVERED-WIRE SEAL AND COVERED WIRE 東亞合成株式会社 2021-04-01 WO disclosed
CN-107250302-B 2-cyanoacrylate-based adhesive composition 东亚合成株式会社 2021-02-26 CN disclosed
US-10647888-B2 2-cyanoacrylate adhesive composition TOAGOSEI CO., LTD. (JP) 2020-05-12 US disclosed
EP-2067782-B2 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS TOSOH CORP (JP) 2018-06-27 EP disclosed
US-20180037772-A1 2-CYANOACRYLATE ADHESIVE COMPOSITION TOAGOSEI CO., LTD. (JP) 2018-02-08 US disclosed
EP-3260509-A1 2-CYANOACRYLATE ADHESIVE COMPOSITION Toagosei Co., Ltd. (JP) 2017-12-27 EP disclosed
CN-107250302-A 2 cyanoacrylate system adhesive compositions 东亚合成株式会社 2017-10-13 CN disclosed
EP-2067782-B1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS TOSOH CORP (JP) 2014-08-13 EP disclosed
US-8138355-B2 Heteroacene derivative, tetrahaloterphenyl derivative, and processes for producing the same TOSOH CORPORATION (JP) 2012-03-20 US disclosed
US-20090261300-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME TOSOH CORPORATION (JP) 2009-10-22 US disclosed
EP-2067782-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS Tosoh Corporation (JP) 2009-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090261300-A1 HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING THE SAME AS3MT, TERT, TEAD1 ALOX15 2053/4885TDP1 2059/4885ALDH1A1 2196/4885
US-10647888-B2 2-cyanoacrylate adhesive composition COL2A1, COL14A1, ICAM1 ALOX15 712/4885TDP1 3281/4885ALDH1A1 288/4885
US-20180037772-A1 2-CYANOACRYLATE ADHESIVE COMPOSITION COL2A1, COL14A1, ICAM1 ALOX15 712/4885TDP1 3281/4885ALDH1A1 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.