Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037935 | 0.76 | POLB (0.62) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL28569270 | 0.76 | POLB (0.62) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL29366939 | 0.75 | MAOB (0.51) | POLBKMT2APTPN1CA1CA2 | |
| SCHEMBL2525949 | 0.75 | MAOB (0.51) | POLBKMT2APTPN1CA1CA2 | |
| SCHEMBL11872015 | 0.73 | PTPN1 (1.00) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL11869804 | 0.73 | POLB (0.59) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL29950744 | 0.73 | PTPN1 (1.00) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL11483748 | 0.73 | ALDH1A1 (0.51) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL15398189 | 0.72 | KMT2A (0.60) | KMT2ACA1CA2ALDH1A1KDM4E | |
| SCHEMBL21591554 | 0.72 | POLB (0.57) | POLBKMT2AMEN1PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151180-A | INTERMEDIATES FOR ANTIALLERGENS, ANTIHISTAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-24 | — | — | US | claimed |