Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550671 | 0.92 | SLC22A12 (0.64) | SLC22A12CYP2C9CYP2C19EYA3MAPT | |
| SCHEMBL11556111 | 0.84 | CYP2C19 (0.60) | SLC22A12CYP2C9CYP2C19TTREYA3 | |
| SCHEMBL11555915 | 0.83 | SLC22A12 (0.52) | SLC22A12CYP2C19EYA3ALDH1A1L3MBTL1 | |
| SCHEMBL1287565 | 0.81 | SLC22A12 (0.88) | SLC22A12CYP2C9CYP2C19TTREYA3 | |
| SCHEMBL11552784 | 0.81 | SLC22A12 (0.51) | SLC22A12CYP2C9CYP2C19TTREYA3 | |
| SCHEMBL11553196 | 0.81 | SLC22A12 (0.50) | SLC22A12CYP2C9CYP2C19TTREYA3 | |
| SCHEMBL11556805 | 0.79 | STAT3 (0.45) | SLC22A12CYP2C19MAPTALDH1A1CA1 | |
| SCHEMBL1287454 | 0.78 | SLC22A12 (1.00) | SLC22A12CYP2C9CYP2C19TTREYA3 | |
| SCHEMBL11555834 | 0.78 | CA2 (0.55) | MAPTALDH1A1GAAL3MBTL1CA1 | |
| SCHEMBL940166 | 0.77 | MMP2 (0.60) | MAPTALDH1A1GAAL3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |