Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567731 | 0.89 | HTR2A (0.53) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8575954 | 0.89 | HTR2A (0.53) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8572360 | 0.86 | HTR2A (0.54) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL8537739 | 0.84 | RAB9A (0.56) | MEN1KMT2AHDAC8HDAC1THRA | |
| SCHEMBL1435371 | 0.82 | HPGDS (0.54) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL31605249 | 0.82 | HPGDS (0.54) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL11653400 | 0.82 | THRB (0.47) | MEN1KMT2APOLBHDAC8HDAC1 | |
| SCHEMBL11654830 | 0.82 | THRB (0.47) | MEN1KMT2APOLBHDAC8HDAC1 | |
| SCHEMBL2558521 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2APOLBHDAC8HDAC1 | |
| SCHEMBL1441802 | 0.81 | KMT2A (0.49) | MEN1KMT2AHDAC8HDAC1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171378-A | INSECTICIDES, VIRICIDES | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |