Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556325 | 0.86 | TSHR (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11557137 | 0.85 | ALOX15 (0.46) | P2RX7ALDH1A1MEN1KMT2A | |
| SCHEMBL11561701 | 0.85 | MCL1 (0.36) | ALDH1A1 | |
| SCHEMBL11564389 | 0.83 | AKR1B1 (0.36) | ALDH1A1KMT2A | |
| SCHEMBL11558455 | 0.80 | RIPK1 (0.37) | RORC | |
| SCHEMBL29456205 | 0.62 | NOTUM (0.50) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3782479 | 0.62 | NOTUM (0.50) | ALDH1A1MEN1KMT2A | |
| SCHEMBL537789 | 0.62 | POLB (0.53) | ALDH1A1RORCMEN1KMT2A | |
| SCHEMBL4971621 | 0.61 | KMO (0.42) | ALDH1A1RORCMEN1KMT2APTGDR2 | |
| SCHEMBL13330275 | 0.61 | CYP11B1 (0.50) | MEN1KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |