Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556325 | 0.86 | TSHR (0.42) | ALDH1A1GAATSHRKMT2AL3MBTL1 | |
| SCHEMBL11558455 | 0.86 | RIPK1 (0.37) | KDM4E | |
| SCHEMBL11557137 | 0.85 | ALOX15 (0.46) | ALDH1A1TSHRPOLBKMT2AALOX15 | |
| SCHEMBL11561701 | 0.85 | MCL1 (0.36) | AKR1B1ALDH1A1GAATSHRPOLB | |
| SCHEMBL11554946 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TSHRPOLBKMT2AL3MBTL1 | |
| SCHEMBL11555657 | 0.83 | P2RX7 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL10443950 | 0.62 | HCRTR2 (0.48) | AKR1B1HCRTR2 | |
| SCHEMBL15964523 | 0.56 | PDE3B (0.40) | ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL13073825 | 0.56 | HCRTR2 (0.47) | AKR1B1HCRTR2 | |
| SCHEMBL12828184 | 0.56 | XIAP (0.50) | ALDH1A1KDM4EPOLBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |