Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556325 | 0.89 | TSHR (0.42) | HSD17B10MAPTHTTTSHRUSP2 | |
| SCHEMBL11561701 | 0.88 | MCL1 (0.36) | ALOX15HSD17B10TSHRUSP2LMNA | |
| SCHEMBL11554946 | 0.86 | ALDH1A1 (0.36) | TSHRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11564389 | 0.85 | AKR1B1 (0.36) | ALOX15HSD17B10TSHRALDH1A1POLB | |
| SCHEMBL11555657 | 0.85 | P2RX7 (0.38) | ALDH1A1MEN1KMT2AP2RX7 | |
| SCHEMBL11558455 | 0.83 | RIPK1 (0.37) | — | |
| SCHEMBL22777623 | 0.63 | POLB (0.60) | ALOX15HSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL9369581 | 0.62 | ATAD2 (0.55) | MAPTTSHRLMNAALDH1A1POLB | |
| SCHEMBL24022881 | 0.61 | ALOX15 (0.54) | ALOX15HSD17B10MAPTHTTTSHR | |
| SCHEMBL10509893 | 0.61 | PTGDR2 (0.48) | ALOX15HSD17B10KMOLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |