Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.52 |
| ▸ | CA2 | P00918 | 16/20 | 0.52 |
| ▸ | CA7 | P43166 | 16/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 16/20 | 0.52 |
| ▸ | CA12 | O43570 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 8/20 | 0.52 |
| ▸ | CA6 | P23280 | 8/20 | 0.52 |
| ▸ | CA3 | P07451 | 6/20 | 0.52 |
| ▸ | CA4 | P22748 | 6/20 | 0.52 |
| ▸ | CA5A | P35218 | 6/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557298 | 0.88 | CA1 (0.54) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11554821 | 0.86 | MMP2 (0.50) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11563025 | 0.82 | CNR2 (0.64) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11555434 | 0.79 | CA1 (0.50) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11555047 | 0.78 | MMP2 (0.53) | CA1CA2CA7CA13CA12 | |
| SCHEMBL6705834 | 0.74 | HTT (0.49) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL11553460 | 0.73 | TSHR (0.46) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11556058 | 0.73 | TSHR (0.45) | CA1CA2CA7CA13CA12 | |
| SCHEMBL940938 | 0.73 | MMP2 (0.54) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11554835 | 0.73 | ACLY (0.43) | CA1CA2CA7CA13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |