Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 13/20 | 0.52 |
| ▸ | CA2 | P00918 | 13/20 | 0.52 |
| ▸ | CA7 | P43166 | 11/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 11/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA3 | P07451 | 4/20 | 0.52 |
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | CA6 | P23280 | 4/20 | 0.52 |
| ▸ | CA5A | P35218 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554821 | 0.87 | MMP2 (0.50) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11558589 | 0.86 | ALDH1A1 (0.47) | MMP2CA1CA2CA12CA9 | |
| SCHEMBL11559300 | 0.86 | RORC (0.43) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11563025 | 0.85 | CNR2 (0.64) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11557298 | 0.85 | CA1 (0.54) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11552491 | 0.82 | ALDH1A1 (0.44) | CA1CA2CA12CA9MAPT | |
| SCHEMBL11555434 | 0.82 | CA1 (0.50) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11559995 | 0.80 | MAPT (0.53) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL940938 | 0.79 | MMP2 (0.54) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11557285 | 0.78 | CA1 (0.52) | MMP2CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |