Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559300 | 0.88 | RORC (0.43) | ACLYTSHRKDM4EGSTO1NPSR1 | |
| SCHEMBL11553460 | 0.87 | TSHR (0.46) | ACLYTSHRL3MBTL1KDM4ENPSR1 | |
| SCHEMBL11554821 | 0.87 | MMP2 (0.50) | TSHRL3MBTL1KDM4EHSD17B10CA12 | |
| SCHEMBL11556058 | 0.76 | TSHR (0.45) | TSHRL3MBTL1KDM4ENPSR1MAPT | |
| SCHEMBL11554724 | 0.75 | PRNP (0.45) | ACLYGSTO1HTTMAPTHSD17B10 | |
| SCHEMBL11555047 | 0.74 | MMP2 (0.53) | MAPTPOLBCA12CA1CA2 | |
| SCHEMBL11554622 | 0.73 | GSTO1 (0.41) | ACLYL3MBTL1KDM4EGSTO1NPSR1 | |
| SCHEMBL11554345 | 0.73 | POLB (0.47) | GSTO1NPSR1HTTMAPTHSD17B10 | |
| SCHEMBL11553624 | 0.73 | CYP2C19 (0.53) | GSTO1HTTMAPTHSD17B10POLB | |
| SCHEMBL11555434 | 0.73 | CA1 (0.50) | KDM4EHSD17B10CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |