SCHEMBL17726870

SCHEMBL17726870

O=C1OC(=O)c2ccc(Oc3cccc(C(F)(F)F)c3)c3cccc1c23

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ TYMS P04818 3/20 0.42
▸ POLB P06746 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ BCL2 P10415 2/20 0.40
▸ MCL1 Q07820 2/20 0.40
▸ ICAM1 P05362 1/20 0.39
▸ SELE P16581 1/20 0.39
▸ EPAS1 Q99814 1/20 0.39
▸ ABCG2 Q9UNQ0 1/20 0.39
▸ KIF11 P52732 1/20 0.39
▸ BRD4 O60885 1/20 0.39
▸ STK39 Q9UEW8 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.38
▸ CYP1A2 P05177 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875713 0.84 L3MBTL1 (0.48) MAPTL3MBTL1NPSR1TYMSPOLB
Trifluoromethanesulfonic Acid SCHEMBL17726889 0.79 KIF11 (0.41) MAPTL3MBTL1NPSR1POLBMEN1
SCHEMBL30678538 0.79 MASP2 (0.53) MAPTL3MBTL1NPSR1TYMSPOLB
SCHEMBL10416155 0.78 KIF11 (0.50) MAPTL3MBTL1POLBKIF11ALDH1A1
SCHEMBL11558315 0.77 TYMS (0.42) MAPTTYMSPOLBMEN1KMT2A
SCHEMBL17726879 0.76 EPAS1 (0.38) MAPTL3MBTL1NPSR1POLBMEN1
SCHEMBL6937952 0.75 TYMS (0.60) MAPTL3MBTL1TYMSPOLBMEN1
SCHEMBL23430836 0.74 MCL1 (0.56) MAPTTYMSPOLBMEN1KMT2A
SCHEMBL16291732 0.73 TYMS (0.53) MAPTTYMSPOLBMEN1KMT2A
SCHEMBL17726919 0.72 TYMS (0.49) MAPTTYMSPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160368879-A1 PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY SAN-APRO LTD. (JP) 2016-12-22 — — US disclosed
EP-3018182-A1 PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY San-Apro Limited (JP) 2016-05-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368879-A1 PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY ARL1, GARS1, SPTBN1 MAPT 3571/4885L3MBTL1 517/4885NPSR1 1423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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