Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554982 | 0.90 | NR3C1 (0.40) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL11556914 | 0.90 | NPC1 (0.39) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL11557128 | 0.89 | SMN1; SMN2 (0.39) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL11556509 | 0.89 | LMNA (0.42) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL11559600 | 0.88 | LMNA (0.40) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL11562119 | 0.86 | MTNR1A (0.45) | NQO2MTNR1AMTNR1B | |
| SCHEMBL11556804 | 0.86 | NPC1 (0.55) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL11558572 | 0.85 | RORC (0.44) | LMNANPC1RAB9ANPSR1TP53 | |
| SCHEMBL11553954 | 0.85 | RORC (0.39) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL11560505 | 0.84 | RORC (0.40) | LMNANPC1RAB9ANPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169931-A | PROCESS FOR THE PREPARATION OF (THIO)HYDANTOINS SUBSTITUTED WITH AMIDE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-10-02 | — | — | US | disclosed |
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |