Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554982 | 0.86 | NR3C1 (0.40) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11556914 | 0.86 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11558484 | 0.86 | PDK1 (0.43) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11557128 | 0.85 | SMN1; SMN2 (0.39) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11556509 | 0.85 | LMNA (0.42) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11559600 | 0.84 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11558572 | 0.84 | RORC (0.44) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11562119 | 0.83 | MTNR1A (0.45) | GAAPOLBMTNR1AMEN1KMT2A | |
| SCHEMBL11553954 | 0.82 | RORC (0.39) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11560505 | 0.80 | RORC (0.40) | NPC1RAB9ASMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |