SCHEMBL11558488

SCHEMBL11558488

CS(=O)(=O)c1cccc(C(=O)O)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
KDM4E B2RXH2 2/20 0.55
HPGD P15428 2/20 0.55
HSD17B10 Q99714 1/20 0.55
MMP2 P08253 2/20 0.50
ALOX15 P16050 2/20 0.50
ALB P02768 1/20 0.50
BCAT2 O15382 1/20 0.49
HNF4A P41235 1/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
HMGB1 P09429 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TSHR P16473 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296105 0.82 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDHSD17B10MMP2
SCHEMBL30640363 0.82 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDHSD17B10MMP2
SCHEMBL34748 0.82 BCAT2 (0.62) ALDH1A1KDM4EHPGDMMP2ALOX15
SCHEMBL29838630 0.82 BCAT2 (0.62) ALDH1A1KDM4EHPGDMMP2ALOX15
SCHEMBL30527264 0.81 ENPP2 (0.42) ALDH1A1HPGDHSD17B10MMP2ALOX15
SCHEMBL3176518 0.81 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDHSD17B10MMP2
Ammonia Solution, Strong SCHEMBL10686249 0.81 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDHSD17B10MMP2
Water SCHEMBL9316143 0.81 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDHSD17B10MMP2
SCHEMBL8962407 0.81 ALOX15 (0.50) ALDH1A1KDM4EHPGDHSD17B10MMP2
Water SCHEMBL6715460 0.81 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDHSD17B10MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4146631-A ANTIALLERGENS, RESPIRATORY DISORDERS MAY & BAKER LIMITED (GB) 1979-03-27 US disclosed