Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.39 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788696 | 0.81 | ALDH1A1 (0.53) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL9340912 | 0.79 | ALDH1A1 (0.59) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL9680940 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL9810876 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL9441416 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL316680 | 0.75 | ALDH1A1 (0.59) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL7523538 | 0.74 | ALDH1A1 (0.46) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL10626842 | 0.73 | ALOX15 (0.61) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL20680463 | 0.73 | ALDH1A1 (0.57) | ALDH1A1ALOX15NR1I2LMNACYP2C9 | |
| SCHEMBL7523766 | 0.73 | ALDH1A1 (0.44) | ALDH1A1ALOX15NR1I2LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143076-A | MERCAPTO PHENOLIC AND ALKYLTHIO PHENOLIC ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4128530-A | Mercapto phenolic and alkylthio phenolic antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-12-05 | — | — | US | disclosed |