Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.39 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405742 | 0.81 | ALOX15 (0.53) | ALDH1A1ALOX15CYP2C9LMNATYR | |
| SCHEMBL9788696 | 0.81 | ALDH1A1 (0.53) | ALDH1A1ALOX15CYP2C9NR1I2LMNA | |
| SCHEMBL11560736 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15CYP2C9NR1I2LMNA | |
| SCHEMBL9810876 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ALOX15CYP2C9NR1I2LMNA | |
| SCHEMBL9441416 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ALOX15CYP2C9NR1I2LMNA | |
| SCHEMBL11611680 | 0.75 | MAOA (0.48) | ALDH1A1ALOX15CYP2C9NR1I2LMNA | |
| SCHEMBL9340912 | 0.75 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP2C9NR1I2LMNA | |
| SCHEMBL316680 | 0.75 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP2C9NR1I2LMNA | |
| SCHEMBL7523538 | 0.74 | ALDH1A1 (0.46) | ALDH1A1ALOX15CYP2C9NR1I2LMNA | |
| SCHEMBL10626842 | 0.73 | ALOX15 (0.61) | ALDH1A1ALOX15CYP2C9NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019591-A1 | PROCESS FOR PREPARATION OF ALPHA-ALKOXY ACETIC ACIDS AND THEIR SALTS | G.D. SEARLE & CO. (US) | 1992-11-12 | — | — | WO | disclosed |
| EP-0512472-A1 | Process for preparation of alpha-alkoxy acetic acids and their salts | G.D. Searle & Co. (US) | 1992-11-11 | — | — | EP | disclosed |
| US-5145992-A | Oxyalkylation of an alcohol, reaction with monoaloacetic acid and then with hydrochloic acid | G. D. SEARLE & CO. (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0434896-A1 | Process for preparation of alpha-alkoxy acetic acids and their salts | G.D. Searle & Co. (US) | 1991-07-03 | — | — | EP | disclosed |
| EP-0431248-A1 | Process for preparation of alpha-aryloxy acetic acids and their salts | G.D. Searle & Co. (US) | 1991-06-12 | — | — | EP | disclosed |
| US-5013864-A | From alcohol and haloacetic acid salt | G. D. SEARLE & CO. (US) | 1991-05-07 | — | — | US | disclosed |