Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29603325 | 0.85 | MAPT (0.59) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL152563 | 0.85 | MAPT (0.59) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL870485 | 0.84 | NPC1 (0.52) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL18663736 | 0.84 | RAB9A (0.54) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL28776139 | 0.83 | MAPT (0.58) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL14333373 | 0.83 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7469868 | 0.83 | MAPT (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27617245 | 0.83 | MAPT (0.58) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL9191986 | 0.83 | MAPT (0.58) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4229730 | 0.83 | MAPT (0.58) | NPC1RAB9AALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080427-A1 | METHOD FOR PRODUCING UV-ABSORBING HYBRID MATERIALS | BASF SE (DE) | 2009-07-02 | — | — | WO | claimed |
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | MERCK PATENT GMBH (DE) | 2004-05-27 | — | — | US | claimed |
| EP-3663366-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2025-01-08 | — | — | EP | disclosed |
| EP-3675809-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | BASF SE (DE) | 2022-09-06 | — | — | US | disclosed |
| US-11044931-B2 | Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof | BASF SE (DE) | 2021-06-29 | — | — | US | disclosed |
| EP-2758041-B1 | LOW-MOLECULAR MODULATORS OF THE COLD-MENTHOL RECEPTOR TRPM8 AND USE OF SAME | BASF SE (DE) | 2021-01-13 | — | — | EP | disclosed |
| EP-3675809-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-07-08 | — | — | EP | disclosed |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-06-18 | — | — | US | disclosed |
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-3663366-A2 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | Symrise AG (DE) | 2020-06-10 | — | — | EP | disclosed |
| EP-0945125-A1 | Cosmetic and pharmaceutical compositions containing photostable uv filters | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| CN-1224032-A | Use of isoindolinone derivatives as stabilizers for organic materials | BASF AG (DE) | 1999-07-28 | — | — | CN | disclosed |
| EP-0924246-A1 | Uses of Isoindolinone derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-23 | — | — | EP | disclosed |
| CN-1218806-A | Sorbic acid vitamin C ester | BASF AG (DE) | 1999-06-09 | — | — | CN | disclosed |
| EP-0917871-A2 | Cosmetic and pharmaceutical compositions comprising ascorbic acid derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-26 | — | — | EP | disclosed |
| EP-0916662-A2 | Ascorbylsorbate | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-19 | — | — | EP | disclosed |
| EP-0911020-A1 | Methylstyrene derivatives as UV-filters and cosmetic and pharmaceutical preparations containing them | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-28 | — | — | EP | disclosed |
| EP-0852137-A2 | Cosmetic compositions containing a photostable UV-A filter | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-08 | — | — | EP | disclosed |
| EP-0826361-A1 | Cosmetical preparations containing photostable UV-A filters | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | TRPM8, TRPM7, TRPM5 | NPC1 708/4885RAB9A 3290/4885ALDH1A1 1810/4885 |
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | CUTA, CYP1B1, TPH1 | NPC1 3313/4885RAB9A 1776/4885ALDH1A1 289/4885 |
| US-11044931-B2 | Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof | TRPM8, TRPM7, TRPM2 | NPC1 2315/4885RAB9A 2487/4885ALDH1A1 3977/4885 |
| US-20200190052-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | TRPM8, TRPM7, TRPM5 | NPC1 708/4885RAB9A 3290/4885ALDH1A1 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.