Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPME1 | Q9Y570 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557463 | 0.79 | LMNA (0.52) | LMNAKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL5635633 | 0.78 | MAPT (0.52) | PKML3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL5635627 | 0.78 | MAPT (0.52) | PKML3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL29289226 | 0.74 | PKM (0.74) | PKML3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL29289222 | 0.74 | PKM (0.74) | PKML3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL11567419 | 0.72 | LMNA (0.46) | LMNASMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL11565045 | 0.72 | ALDH1A1 (0.44) | PKML3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL10716495 | 0.72 | GAA (0.46) | PKMLMNAHPGDKDM4EMAPT | |
| SCHEMBL29289223 | 0.72 | PKM (0.65) | PKML3MBTL1LMNAHPGDALDH1A1 | |
| SCHEMBL29289227 | 0.72 | PKM (0.65) | PKML3MBTL1LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |