Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PPME1 | Q9Y570 | 3/20 | 0.44 |
| ▸ | APEH | P13798 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL6 | P05231 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567419 | 0.81 | LMNA (0.46) | LMNASMN1; SMN2NFKB1MEN1KMT2A | |
| SCHEMBL11563623 | 0.79 | PKM (0.46) | LMNASMN1; SMN2PPME1MEN1KMT2A | |
| SCHEMBL11580970 | 0.78 | PPME1 (0.48) | LMNASMN1; SMN2PPME1APEHMEN1 | |
| SCHEMBL11563828 | 0.77 | PPME1 (0.47) | LMNASMN1; SMN2PPME1APEHMEN1 | |
| SCHEMBL11562973 | 0.77 | TRPA1 (0.57) | PPME1APEHMEN1KMT2AKDM4E | |
| SCHEMBL3368306 | 0.76 | TRPA1 (0.55) | LMNASMN1; SMN2NFKB1MEN1KMT2A | |
| SCHEMBL11567151 | 0.75 | KDM4E (0.58) | LMNAPPME1APEHMEN1KMT2A | |
| SCHEMBL10986168 | 0.75 | NFKB1 (0.47) | LMNASMN1; SMN2NFKB1MEN1KMT2A | |
| SCHEMBL4661446 | 0.73 | LMNA (0.61) | LMNASMN1; SMN2NFKB1KMT2AMAOB | |
| SCHEMBL4661444 | 0.73 | LMNA (0.61) | LMNASMN1; SMN2NFKB1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |