Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716561 | 0.77 | CASP3 (0.52) | GAAKMT2ALMNAPKMHPGD | |
| SCHEMBL10717698 | 0.73 | MAPT (0.72) | GAAKMT2ALMNAPKMMAPT | |
| SCHEMBL11563623 | 0.72 | PKM (0.46) | GAAKMT2ALMNAPKMHPGD | |
| SCHEMBL1465187 | 0.69 | CNR2 (0.65) | GAAKMT2AGRIK1CNR1 | |
| SCHEMBL28234385 | 0.68 | KDM4E (0.48) | GAAKMT2AMAPTGRIK1KDM4E | |
| SCHEMBL10725846 | 0.68 | ALDH1A1 (0.54) | GAAKMT2ALMNAPKMMAPT | |
| SCHEMBL10718981 | 0.67 | ALDH1A1 (0.43) | GAAKMT2ALMNAMAPTHTT | |
| SCHEMBL10726650 | 0.67 | MEN1 (0.53) | GAAKMT2ALMNAMAPTKDM4E | |
| SCHEMBL28312427 | 0.66 | HSD11B1 (0.61) | KMT2ASLC22A12 | |
| SCHEMBL2096095 | 0.66 | POLB (0.53) | GAAKMT2AMAPTSLC22A12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |