Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598756 | 0.82 | ALDH1A1 (0.55) | NPC1POLBATMMEN1KMT2A | |
| SCHEMBL11773236 | 0.82 | KDM4E (0.66) | NPC1POLBCASP3SENP7SENP6 | |
| SCHEMBL11775723 | 0.82 | KDM4E (0.60) | NPC1POLBCASP3SENP7SENP6 | |
| SCHEMBL11662821 | 0.81 | NPC1 (0.52) | NPC1POLBCASP3SENP7SENP6 | |
| SCHEMBL11657935 | 0.80 | MEN1 (0.64) | NPC1POLBCASP3SENP7SENP6 | |
| SCHEMBL11665696 | 0.80 | MAPT (0.55) | NPC1POLBCASP3SENP7SENP6 | |
| SCHEMBL11771377 | 0.80 | ALDH1A1 (0.57) | NPC1POLBCASP3SENP7SENP6 | |
| SCHEMBL11776026 | 0.78 | MAPT (0.49) | NPC1POLBCASP3SENP7SENP6 | |
| SCHEMBL11664267 | 0.78 | RAB9A (0.52) | NPC1POLBATMMEN1KMT2A | |
| SCHEMBL11598294 | 0.78 | PPARG (0.45) | NPC1POLBCASP3SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144258-A | ORGANIC PIGMENTS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4065481-A | 1:1-Azomethine-metal-complex dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-3988323-A | PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |