Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CBR1 | P16152 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662821 | 0.92 | NPC1 (0.52) | PPARGPTGESARCBR1AKR1C3 | |
| SCHEMBL11776026 | 0.89 | MAPT (0.49) | PPARGPTGESARCBR1AKR1C3 | |
| SCHEMBL11770628 | 0.87 | NPC1 (0.53) | PTGESMEN1KMT2AMAPTNPC1 | |
| SCHEMBL11663687 | 0.84 | RAB9A (0.48) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL11664267 | 0.84 | RAB9A (0.52) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL11624948 | 0.82 | ALDH1A1 (0.51) | AKR1C3MEN1KMT2AMAPTNPC1 | |
| SCHEMBL11430394 | 0.80 | MEN1 (0.56) | AKR1C3MEN1KMT2AMAPTNPC1 | |
| SCHEMBL11561031 | 0.80 | MAPT (0.52) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL11775723 | 0.79 | KDM4E (0.60) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL11773236 | 0.79 | KDM4E (0.66) | MEN1KMT2AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072700-A | Azomethine copper complexes | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |