Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 4/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3192546 | 0.77 | SRD5A2 (0.58) | FFAR1NPC1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL9296304 | 0.76 | L3MBTL1 (0.65) | FFAR1ALDH1A1CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL10825738 | 0.76 | ESRRA (0.68) | ESRRAFFAR1TSHRLMNANPC1 | |
| SCHEMBL6446114 | 0.75 | KMT2A (0.56) | LMNANPC1RAB9AALDH1A1CYP4F2 | |
| SCHEMBL5000233 | 0.75 | LMNA (0.55) | ESRRATSHRLMNANPC1RAB9A | |
| SCHEMBL11565999 | 0.74 | ESRRA (0.58) | ESRRAFFAR1TSHRLMNANPC1 | |
| SCHEMBL27305578 | 0.73 | ALDH1A1 (0.48) | LMNANPC1RAB9AALDH1A1CYP4F2 | |
| SCHEMBL6242055 | 0.73 | NCOA1 (0.51) | FFAR1LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL5204961 | 0.71 | L3MBTL1 (0.51) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL4113212 | 0.71 | CYP4F2 (0.76) | LMNANPC1RAB9AALDH1A1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |