Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431722 | 0.78 | LMNA (0.43) | LMNAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL23009201 | 0.78 | RAB9A (0.63) | LMNAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL399012 | 0.76 | GAA (0.50) | LMNAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL1647598 | 0.73 | NFKB1 (0.49) | MAPTSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL8222555 | 0.73 | LMNA (0.59) | LMNAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11347574 | 0.72 | MAPT (0.51) | LMNAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11563626 | 0.70 | HDAC3 (0.45) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6179675 | 0.70 | GAA (0.48) | LMNAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL7654224 | 0.69 | RAB9A (0.51) | LMNAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL1163822 | 0.69 | CTSK (0.60) | LMNAMAPTSMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165315-A | CHLORINATION WITH AN N-CHLORO HALOGENATING AGENT | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4165316-A | Process for preparing sulfinyl chlorides from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4081440-A | Sulfinyl halides and their preparation from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4075203-A | Process for preparing a 3-exomethylenecepham sulfoxide from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4008231-A | Preparation of 3-methoxymethylcephalosporins | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |