Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 6/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 6/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148987 | 0.83 | NPFFR1 (0.61) | NPFFR1NPFFR2OPRM1OPRD1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11565432 | 0.82 | NPFFR1 (0.60) | NPFFR1NPFFR2OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL781667 | 0.80 | OPRM1 (0.55) | NPFFR1NPFFR2OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL11564641 | 0.79 | NPFFR1 (0.53) | NPFFR1NPFFR2SMN1; SMN2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11563478 | 0.79 | OPRM1 (0.54) | NPFFR1NPFFR2OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL11569035 | 0.78 | DRD2 (0.46) | NPFFR1NPFFR2OPRM1SIGMAR1 | |
| SCHEMBL11568672 | 0.78 | NPFFR1 (0.44) | NPFFR1NPFFR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11566633 | 0.78 | NPFFR1 (0.45) | NPFFR1NPFFR2OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL11566486 | 0.78 | SIGMAR1 (0.55) | NPFFR1NPFFR2OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL11566955 | 0.78 | NPFFR1 (0.53) | NPFFR1NPFFR2OPRM1OPRD1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |