Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564349 | 0.81 | HSD17B10 (0.48) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL6824878 | 0.74 | MEN1 (0.67) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL11567837 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL12114202 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL11564817 | 0.71 | PDE9A (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL11562611 | 0.71 | GRIA2 (0.37) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL295307 | 0.70 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL9148849 | 0.70 | NR4A1 (0.52) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL9158144 | 0.69 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| Methane SCHEMBL28696439 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180666-A | 3,9-Dihydro-3,9-dioxo-2H-indeno(2,1-c)-pyridine-4-(carbonitriles/carboxamides) | G. D. SEARLE & CO. (US) | 1979-12-25 | — | — | US | disclosed |