Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139060 | 0.84 | HPGD (0.42) | MAPTKDM4EGAAHPGDTNKS2 | |
| SCHEMBL27767819 | 0.81 | DCLRE1A (0.43) | SMN1; SMN2LMNAHTTRAB9AMAPT | |
| SCHEMBL21753292 | 0.81 | QDPR (0.41) | SMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL31490983 | 0.80 | ERBB2 (0.41) | SMN1; SMN2LMNAHTTRAB9AHSD17B1 | |
| SCHEMBL17281581 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAHTTRAB9AHSD17B1 | |
| SCHEMBL3174141 | 0.80 | DCLRE1B (0.51) | SMN1; SMN2LMNAHTTRAB9AHSD17B1 | |
| SCHEMBL5263743 | 0.80 | PDCD1 (0.48) | SMN1; SMN2LMNAHTTRAB9AHSD17B1 | |
| SCHEMBL2571211 | 0.80 | TAAR1 (0.48) | SMN1; SMN2LMNAHTTRAB9AHSD17B1 | |
| SCHEMBL21770153 | 0.79 | MKNK1 (0.52) | CYP1A2 | |
| SCHEMBL455471 | 0.78 | MAPT (0.40) | SMN1; SMN2LMNAHTTRAB9AHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180670-A | Amino pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-12-25 | — | — | US | disclosed |