Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 3/20 | 0.51 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17281581 | 0.80 | SMN1; SMN2 (0.41) | LMNAHTTRAB9ASMN1; SMN2HSD17B1 | |
| SCHEMBL5263743 | 0.80 | PDCD1 (0.48) | DCLRE1BDCLRE1ALMNAHTTRAB9A | |
| SCHEMBL31490983 | 0.80 | ERBB2 (0.41) | LMNAHTTRAB9ASMN1; SMN2HSD17B1 | |
| SCHEMBL2571211 | 0.80 | TAAR1 (0.48) | LMNAHTTRAB9ASMN1; SMN2HSD17B1 | |
| SCHEMBL11565504 | 0.80 | SMN1; SMN2 (0.41) | LMNAHTTRAB9ASMN1; SMN2HSD17B1 | |
| SCHEMBL455471 | 0.78 | MAPT (0.40) | LMNAHTTRAB9ASMN1; SMN2HSD17B1 | |
| SCHEMBL23403331 | 0.77 | CYP1A2 (0.39) | LMNAHTTRAB9ASMN1; SMN2HSD17B1 | |
| SCHEMBL19193982 | 0.77 | LMNA (0.39) | LMNAHTTRAB9ASMN1; SMN2HSD17B1 | |
| SCHEMBL19200643 | 0.76 | DCLRE1B (0.51) | DCLRE1BDCLRE1ALMNAHTTKDM4E | |
| SCHEMBL19199865 | 0.76 | HSD17B10 (0.52) | DCLRE1BDCLRE1ALMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341534-B1 | COMPOUNDS HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO MAKE AND USE SAME | DOW AGROSCIENCES LLC (US) | 2010-03-31 | — | — | EP | disclosed |