SCHEMBL31490983

SCHEMBL31490983

Cc1cc(-c2ccccc2)ccc1CBr

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
RXRA P19793 2/20 0.38
RXRB P28702 2/20 0.38
MAPK1 P28482 1/20 0.38
BRD4 O60885 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11856520 0.89 ALDH1A1 (0.48) ERBB2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL6772346 0.84 GAA (0.42) ERBB2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL5160117 0.81 DCLRE1A (0.43) LMNAHTTALDH1A1CYP3A4TSHR
SCHEMBL2571211 0.80 TAAR1 (0.48) LMNAHTTRAB9ASMN1; SMN2ALDH1A1
SCHEMBL5263743 0.80 PDCD1 (0.48) LMNAHTTRAB9ASMN1; SMN2HSD17B1
SCHEMBL11565504 0.80 SMN1; SMN2 (0.41) LMNAHTTRAB9ASMN1; SMN2HSD17B1
SCHEMBL3174141 0.80 DCLRE1B (0.51) LMNAHTTRAB9ASMN1; SMN2HSD17B1
SCHEMBL17281581 0.80 SMN1; SMN2 (0.41) LMNAHTTRAB9ASMN1; SMN2ALDH1A1
SCHEMBL455471 0.78 MAPT (0.40) LMNAHTTRAB9ASMN1; SMN2ALDH1A1
SCHEMBL3230214 0.78 RXRA (0.50) LMNAALDH1A1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661535-A 7H-pyrrolo [3,2-f ] quinazoline derivatives and anti-infective application thereof 中国医学科学院药物研究所 2025-03-21 CN disclosed