Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690862 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL10863780 | 0.76 | TP53 (0.38) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL7815170 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL7273862 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL1666306 | 0.72 | ALDH1A1 (0.74) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL11500155 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL7818024 | 0.70 | ALDH1A1 (0.62) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL9691613 | 0.70 | ADORA3 (0.49) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL7266747 | 0.70 | KDM4E (0.56) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL7267057 | 0.69 | L3MBTL1 (0.65) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001769-A1 | Sulfur-containing esters of 1,4-dihydropyridine carboxylic acids, their preparation and pharmaceutical use | BAYER AG (DE) | 1979-05-16 | — | — | EP | disclosed |