Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565945 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1PKM | |
| SCHEMBL9690374 | 0.82 | PKM (0.46) | ALDH1A1MAPTKMT2AMEN1PKM | |
| SCHEMBL10375453 | 0.81 | KDM4E (0.44) | ALDH1A1MAPTKMT2AMEN1PKM | |
| SCHEMBL1666306 | 0.81 | ALDH1A1 (0.74) | ALDH1A1MAPTKMT2AMEN1PKM | |
| SCHEMBL9690361 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMEN1PKM | |
| SCHEMBL11500155 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1ADORA2B | |
| SCHEMBL7322941 | 0.77 | ADORA3 (0.58) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL9369030 | 0.72 | CACNA1F (0.49) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL7815170 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AMEN1PKM | |
| SCHEMBL7384754 | 0.72 | ALDH1A1 (0.62) | ALDH1A1MAPTKMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234516-B1 | 1,6-NAPHTHYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINE CONTAINING THEM FOR THE TREATMENT OF VASCULAR DISEASES | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1992-04-29 | — | — | EP | disclosed |
| EP-0234516-A1 | 1,6-Naphthyridine derivatives, process for their preparation and medicine containing them for the treatment of vascular diseases | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1987-09-02 | — | — | EP | disclosed |