Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565474 | 0.81 | EPHX2 (0.33) | LMNAEPHX2NR1H4KDM4EALDH1A1 | |
| SCHEMBL11567347 | 0.75 | ALDH1A1 (0.40) | LMNACNR2KDM4EALDH1A1HPGD | |
| SCHEMBL10583482 | 0.70 | EPHX2 (0.42) | LMNATSHREPHX2NR1H4ALDH1A1 | |
| SCHEMBL10290185 | 0.69 | — | — | |
| SCHEMBL5613238 | 0.69 | — | — | |
| SCHEMBL5487981 | 0.69 | LMNA (0.53) | LMNATSHRKDM4EALDH1A1GAA | |
| SCHEMBL10887450 | 0.69 | MMP8 (0.49) | LMNAALDH1A1KMT2A | |
| SCHEMBL5485596 | 0.67 | MAPK1 (0.35) | TSHRHPGD | |
| SCHEMBL10891030 | 0.67 | ALDH1A1 (0.53) | LMNAEPHX2ALDH1A1GAAKMT2A | |
| SCHEMBL9767852 | 0.67 | NPC1 (0.46) | LMNAALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145362-A | DIAZOTIZATION OF ARYLAMINE IN PRESENCE OF ALKANOIC ACID, COPPER HALIDE CATALYST | S.A. P R B EN NEERLANDAIS PRB N.V. (BE) | 1979-03-20 | — | — | US | disclosed |