Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24375903 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL8651766 | 0.77 | P2RX7 (0.47) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL8801272 | 0.76 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC6P2RX7 | |
| SCHEMBL11566864 | 0.75 | LMNA (0.39) | ALDH1A1LMNACNR2KMT2AKDM4E | |
| SCHEMBL8654003 | 0.75 | P2RX7 (0.43) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL23110659 | 0.74 | ALDH1A1 (0.36) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL9917352 | 0.73 | CYP3A4 (0.39) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL10923842 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL8558450 | 0.72 | ANO1 (0.42) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL13593234 | 0.72 | HDAC3 (0.39) | HDAC3HDAC1HDAC2HDAC6P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145362-A | DIAZOTIZATION OF ARYLAMINE IN PRESENCE OF ALKANOIC ACID, COPPER HALIDE CATALYST | S.A. P R B EN NEERLANDAIS PRB N.V. (BE) | 1979-03-20 | — | — | US | disclosed |