SCHEMBL17065508

SCHEMBL17065508

COC(=O)c1ccc(C(=O)OC)c(C2CCCCC2)c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 5/20 0.45
TSHR P16473 2/20 0.44
SLC6A3 Q01959 3/20 0.44
HSD17B10 Q99714 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
HPGD P15428 1/20 0.44
RECQL P46063 1/20 0.43
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
ALOX12 P18054 1/20 0.41
STS P08842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566905 0.83 KDM4E (0.50) KDM4EALDH1A1TSHRHSD17B10NPSR1
SCHEMBL5951054 0.75 CA12 (0.46) KDM4EALDH1A1TSHRSLC6A3HSD17B10
SCHEMBL1793340 0.73 KDM4E (0.54) KDM4EALDH1A1TSHRHSD17B10NPSR1
SCHEMBL12377184 0.73 TUBB4A (0.39) KDM4EALDH1A1TSHRSLC6A3HSD17B10
SCHEMBL14995173 0.72 CDC7 (0.54) KDM4EALDH1A1TSHRSLC6A3HSD17B10
SCHEMBL898708 0.72 ALDH1A1 (0.53) KDM4EALDH1A1TSHRHSD17B10NPSR1
SCHEMBL27931718 0.71 TSHR (0.55) KDM4EALDH1A1TSHRHSD17B10NPSR1
SCHEMBL7598114 0.71 KDM4E (0.55) KDM4EALDH1A1TSHRHSD17B10NPSR1
SCHEMBL30009936 0.71 CXCR5 (0.50) KDM4EALDH1A1TSHRHSD17B10NPSR1
SCHEMBL28721789 0.70 ACMSD (0.55) KDM4EALDH1A1TSHRHSD17B10NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10434705-B2 Additive manufactured items with flame resistance, process for making and process for testing their flame performance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-08 US claimed
EP-3113934-B1 ADDITIVE MANUFACTURED ITEMS WITH FLAME RESISTANCE, PROCESS FOR MAKING AND PROCESS FOR TESTING THEIR FLAME PERFORMANCE SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-04-11 EP claimed
US-20170072631-A1 ADDITIVE MANUFACTURED ITEMS WITH FLAME RESISTANCE, PROCESS FOR MAKING AND PROCESS FOR TESTING THEIR FLAME PERFORMANCE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-03-16 US claimed
EP-3113934-A1 ADDITIVE MANUFACTURED ITEMS WITH FLAME RESISTANCE, PROCESS FOR MAKING AND PROCESS FOR TESTING THEIR FLAME PERFORMANCE SABIC Global Technologies B.V. (NL) 2017-01-11 EP claimed
WO-2015134316-A1 ADDITIVE MANUFACTURED ITEMS WITH FLAME RESISTANCE, PROCESS FOR MAKING AND PROCESS FOR TESTING THEIR FLAME PERFORMANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-09-11 WO claimed
US-10434705-B2 Additive manufactured items with flame resistance, process for making and process for testing their flame performance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-08 US disclosed
EP-3113934-B1 ADDITIVE MANUFACTURED ITEMS WITH FLAME RESISTANCE, PROCESS FOR MAKING AND PROCESS FOR TESTING THEIR FLAME PERFORMANCE SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-04-11 EP disclosed
US-20170072631-A1 ADDITIVE MANUFACTURED ITEMS WITH FLAME RESISTANCE, PROCESS FOR MAKING AND PROCESS FOR TESTING THEIR FLAME PERFORMANCE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-03-16 US disclosed
EP-3113934-A1 ADDITIVE MANUFACTURED ITEMS WITH FLAME RESISTANCE, PROCESS FOR MAKING AND PROCESS FOR TESTING THEIR FLAME PERFORMANCE SABIC Global Technologies B.V. (NL) 2017-01-11 EP disclosed
WO-2015134316-A1 ADDITIVE MANUFACTURED ITEMS WITH FLAME RESISTANCE, PROCESS FOR MAKING AND PROCESS FOR TESTING THEIR FLAME PERFORMANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-09-11 WO disclosed