Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443826 | 0.83 | GPR35 (0.41) | GPR35CA2CYSLTR2CYSLTR1DGKA | |
| SCHEMBL1156999 | 0.82 | GPR35 (0.49) | GPR35CYP3A4CYP2C19CYP1A2CYP2C8 | |
| SCHEMBL1156737 | 0.77 | CA2 (0.45) | GPR35CA2 | |
| SCHEMBL27942088 | 0.77 | GPR35 (0.45) | GPR35CYSLTR2CYSLTR1 | |
| SCHEMBL5282461 | 0.72 | GPR35 (0.41) | GPR35CYP3A4MAPTKMT2ACYSLTR2 | |
| SCHEMBL1156995 | 0.71 | MAPT (0.37) | CA2MAPTKMT2AALDH1A1 | |
| SCHEMBL10018136 | 0.70 | GPR35 (0.49) | GPR35CA2CYSLTR2CYSLTR1 | |
| SCHEMBL27953945 | 0.70 | GPR35 (0.44) | GPR35CYSLTR2CYSLTR1 | |
| SCHEMBL27943887 | 0.69 | LTB4R (0.46) | GPR35CYSLTR2CYSLTR1 | |
| SCHEMBL27943862 | 0.69 | LTB4R (0.46) | GPR35CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308882-B1 | Fused thiophenes and uses thereof | CORNING INC (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-2773646-B1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2129678-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2015-05-27 | — | — | EP | disclosed |
| US-8846855-B2 | Conjugated fused thiophenes, methods of making conjugated fused thiophenes, and uses thereof | CORNING INCORPORATED (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2773646-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | Corning Incorporated (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2773687-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | Corning Inc. (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-1799688-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2013066732-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2013-05-10 | — | — | WO | disclosed |
| WO-2013066973-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2013-05-10 | — | — | WO | disclosed |
| US-20130109821-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED | 2013-05-02 | — | — | US | disclosed |
| US-20110040042-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | HE MINGQIAN | 2011-02-17 | — | — | US | disclosed |
| US-7838623-B2 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED (US) | 2010-11-23 | — | — | US | disclosed |
| US-7705108-B2 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | HE MINGQIAN | 2010-01-14 | — | — | US | disclosed |
| EP-2129678-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008106019-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2008-09-04 | — | — | WO | disclosed |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | CORNING INCORPORATED | 2007-11-15 | — | — | US | disclosed |
| US-20070161776-A1 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| EP-1799688-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006031893-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040042-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | TPMT, TST, TYMP | GPR35 4429/4885PTGES 240/4885CYP3A4 66/4885 |
| US-20130109821-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | TST, TPMT, TPR | GPR35 4231/4885PTGES 440/4885CYP3A4 299/4885 |
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | TPMT, TST, TYMP | GPR35 4520/4885PTGES 259/4885CYP3A4 62/4885 |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | TPMT, TST, TYMP | GPR35 4429/4885PTGES 240/4885CYP3A4 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.