Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14002893 | 0.80 | IDO1 (0.45) | IDO1PNMTTAAR1PKMNPC1 | |
| SCHEMBL73408 | 0.77 | IDO1 (0.50) | IDO1PNMTTAAR1PKMNPC1 | |
| SCHEMBL11566872 | 0.76 | RAB9A (0.46) | IDO1PNMTTAAR1ALDH1A1NPC1 | |
| SCHEMBL8525795 | 0.74 | IDO1 (0.52) | IDO1PNMTTAAR1PKMNPC1 | |
| Clortermine SCHEMBL30295323 | 0.74 | PNMT (0.52) | IDO1PNMTTAAR1PKMSLC6A2 | |
| SCHEMBL1885793 | 0.74 | IDO1 (0.46) | IDO1PNMTTAAR1PKMNPC1 | |
| SCHEMBL13509534 | 0.74 | IDO1 (0.46) | IDO1PNMTTAAR1PKMALDH1A1 | |
| Clortermine SCHEMBL164137 | 0.74 | PNMT (0.52) | IDO1PNMTTAAR1PKMSLC6A2 | |
| SCHEMBL29628878 | 0.73 | SIGMAR1 (0.41) | IDO1PNMTTAAR1PKMALDH1A1 | |
| Clortermine SCHEMBL266778 | 0.72 | PNMT (0.50) | IDO1PNMTTAAR1PKMSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145362-A | DIAZOTIZATION OF ARYLAMINE IN PRESENCE OF ALKANOIC ACID, COPPER HALIDE CATALYST | S.A. P R B EN NEERLANDAIS PRB N.V. (BE) | 1979-03-20 | — | — | US | disclosed |