Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.45 |
| ▸ | CTSK | P43235 | 9/20 | 0.42 |
| ▸ | CTSL | P07711 | 8/20 | 0.42 |
| ▸ | CTSB | P07858 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568854 | 0.93 | CTSS (0.45) | CTSSCTSKCTSLCTSBALDH1A1 | |
| Dimethylformamide SCHEMBL11567929 | 0.87 | CTSS (0.41) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL25178599 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ABCB1SMN1; SMN2 | |
| SCHEMBL8615972 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ABCB1SMN1; SMN2 | |
| SCHEMBL8615968 | 0.79 | ALDH1A1 (0.47) | ALDH1A1ABCB1SMN1; SMN2 | |
| SCHEMBL11566331 | 0.76 | ALDH1A1 (0.45) | ALDH1A1ABCB1SMN1; SMN2 | |
| SCHEMBL13401595 | 0.75 | ALDH1A1 (0.46) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL11568741 | 0.75 | ALDH1A1 (0.47) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL1285759 | 0.74 | ALDH1A1 (0.51) | ALDH1A1ABCB1SMN1; SMN2 | |
| SCHEMBL23944461 | 0.74 | ALDH1A1 (0.55) | ALDH1A1ABCB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002822-A1 | Phosphorus containing peptide derivatives, their production, intermediates for their production and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | disclosed |