Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401156 | 0.89 | ALDH1A1 (0.54) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL17992013 | 0.77 | MAPT (0.53) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL15399392 | 0.77 | MAPT (0.53) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL17988695 | 0.77 | ALDH1A1 (0.55) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL5242625 | 0.76 | RAB9A (0.61) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL2109107 | 0.76 | RAB9A (0.61) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL11565649 | 0.76 | RAB9A (0.61) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL28990293 | 0.76 | RAB9A (0.61) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL11397717 | 0.75 | ALOX12 (0.45) | MAPTRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL29817357 | 0.75 | CYP11B1 (0.67) | MAPTRAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |
| US-4076729-A | (4-Oxo-4H-1-benzopyran-3-yl)aminooxoacetic acids and their derivatives | WARNER-LAMBERT COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4071625-A | 19-Oxygenated-5α-androstanes for the enhancement of libido | RICHARDSON-MERRELL INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-4071624-A | Androst-4-en-19-ones for the enhancement of libido | RICHARDSON-MERRELL INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-4066655-A | 4,10-Dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-3-carboxylic acids, salts and esters | WARNER-LAMBERT COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4022769-A | LIBIDO ENHANCEMENT | RICHARDSON-MERRELL INC. (US) | 1977-05-10 | — | — | US | disclosed |