SCHEMBL1156863

SCHEMBL1156863

CC(C)(c1ccccc1)c1cccc(OC(=O)O)c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CNR1 P21554 3/20 0.38
CNR2 P34972 3/20 0.38
FABP3 P05413 1/20 0.36
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36
ALDH1A1 P00352 4/20 0.36
ESR1 P03372 1/20 0.36
CYP3A4 P08684 1/20 0.36
ESR2 Q92731 1/20 0.36
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 3/20 0.35
RXRA P19793 2/20 0.35
RXRB P28702 2/20 0.35
HSD17B10 Q99714 1/20 0.35
FGFR1 P11362 1/20 0.35
SRC P12931 1/20 0.35
FGFR2 P21802 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1157031 0.88 TDP1 (0.48) ATMTDP1FABP3FABP4FABP5
SCHEMBL1157161 0.86 FABP4 (0.37) ATMTDP1FABP3FABP4FABP5
SCHEMBL16469182 0.86 TDP1 (0.45) ATMTDP1CNR1CNR2FABP3
SCHEMBL1673996 0.85 TDP1 (0.47) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL247100 0.83 TDP1 (0.40) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL29601094 0.83 TDP1 (0.40) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL1162218 0.83 CYP2C9 (0.46) ATMTDP1ALDH1A1ESR1CYP3A4
SCHEMBL27789482 0.83 CYP1A2 (0.36) ATMTDP1FABP3FABP4FABP5
SCHEMBL1157235 0.82 ALDH1A1 (0.34) ATMTDP1CNR1CNR2FABP3
SCHEMBL5710931 0.81 LMNA (0.44) ALDH1A1KMT2AKDM4EHSD17B10FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-109153776-B Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207846-B Copolycarbonate compositions comprising diglyceride with improved rheological and optical properties 科思创德国股份有限公司 2020-05-19 CN disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
US-8044122-B2 Polycarbonate composition containing UV absorber BAYER MATERIALSCIENCE AG (DE) 2011-10-25 US disclosed
US-7879967-B2 End groups containing alkylsiloxane substituted phenol compounds ; extrusion; molding materials BAYER MATERIALSCIENCE AG (DE) 2011-02-01 US disclosed
US-20090258978-A1 POLYCARBONATE COMPOSITION CONTAINING UV ABSORBER BAYER MATERIALSCIENCE AG (DE) 2009-10-15 US disclosed
US-20090137709-A1 POLYOL-CONTAINING, FLAME-RESISTANT POLYCARBONATES, PROCESSES FOR PREPARING THE SAME AND PRODUCTS CONTAINING THE SAME BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
US-20080249234-A1 Modified Polycarbonates, Polyester Carbonates and Polyesters Having Improved Elongation Behaviour and Flame Resistance BAYER MATERIALSCIENCE AG (DE) 2008-10-09 US disclosed
US-6596840-B1 By reacting diphenol, carbonic acid dieseter and alkylphenol chain terminator using phosphonium salt catalyst; ester interchange BAYER AKTIENGESELLSCHAFT (DE) 2003-07-22 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed
EP-0434998-B1 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof G E PLASTICS JAPAN LTD (JP) 1996-02-07 EP disclosed
US-5459225-A Ester interchange in antioxidant presence IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-10-17 US disclosed
US-5349042-A Ester interchange and dechlorination with carbonation IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-20 US disclosed
EP-0561363-A2 Process for producing polycarbonate IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-22 EP disclosed
US-5187242-A Workable molding materials containing aliphatic carboxylic acids and aromatic diols as monomers, impact strenth, transparency GENERAL ELECTRIC COMPANY (US) 1993-02-16 US disclosed
EP-0434998-A2 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed